How Drugs Induce Profound Changes In Perception?

Drug addiction is a condition, which can cause a lot of difficulty to the person consuming it as well as others around them. We are one of the leading providers of Drugs addiction treatment in Mumbai, as we have access to all the latest tools and technology. We value the trust of the clients, that is the reason why we have become famous all around. Today, in this blog, we are going to shed some light on how drugs induce these profound changes in perception.

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1. Neurotransmitter Disruption

Many drugs that causes hallucinations affect the brain's neurotransmitter systems, which are responsible for communication between neurons.

• Serotonin: Hallucinogenic drugs like LSD, psilocybin (magic mushrooms), and MDMA (ecstasy) primarily affect serotonin receptors. They mimic serotonin or increase its release, leading to altered mood, perception, and cognition.
• Dopamine: Drugs like cocaine and amphetamines increase dopamine levels, which can lead to heightened sensory perception and hallucinations.
• Glutamate: NMDA receptor antagonists like PCP (phencyclidine) and ketamine affect the glutamate system, disrupting normal brain function and leading to dissociative states and hallucinations.

2. Altered Sensory Processing

Drugs can interfere with how sensory information is processed in the brain, leading to hallucinations.

• Thalamus and Cortex Interaction: The thalamus acts as a relay center for sensory information. Hallucinogens can disrupt the normal flow of information between the thalamus and the cortex, causing distorted sensory perceptions.
• Visual Cortex: Drugs affecting the visual cortex can lead to vivid visual hallucinations, such as seeing patterns, colors, or shapes that aren't there.

3. Disrupted Brain Connectivity

Hallucinogenic drugs can alter the connectivity between different regions of the brain, leading to unusual sensory experiences.

• Default Mode Network (DMN): The DMN is involved in self-referential thoughts and daydreaming. Drugs like LSD and psilocybin reduce the activity of the DMN, leading to a breakdown of the sense of self and more vivid hallucinations.
• Hyperconnectivity: Increased connectivity between different brain regions can result in synesthesia, where stimulation of one sensory pathway leads to automatic, involuntary experiences in another pathway (e.g., seeing sounds or hearing colors).

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